TLR2 Antikörper (N-Term)

Produktnummer ABIN7683609

Dieses Kaninchen Polyklonal-Antikörper erkennt spezifisch TLR2 in WB, ELISA, IHC (p) und IF. Er zeigt eine Reaktivität gegenüber Human und Maus.

Kurzübersicht für TLR2 Antikörper (N-Term) (ABIN7683609)

Target: TLR2 (Toll-Like Receptor 2 (TLR2))

Reaktivität: Human, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser TLR2 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (IF)

Produktdetails anti-TLR2 Antikörper

Bindungsspezifität: N-Term

Aufreinigung: TLR2 Antibody is Ion exchange chromatography purified.

Immunogen: TLR2 antibody was raised against a peptide corresponding to 14 amino acids near the amino terminus of human TLR2. The immunogen is located within the first 50 amino acids of TLR2.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: TLR2 antibody can be used for detection of TLR2 by Western blot at 1 μ,g/mL. Despite its predicted molecular weight, TLR2 runs at ~100 kDa in SDS-PAGE. This polyclonal antibody can also detect TLR2 by immunohistochemistry at 2 μ,g/mL. For immunofluorescence start at 10 μ,g/mL.

Antibody validated: Western Blot in mouse samples, Immunohistochemistry in human samples and Immunofluorescence in human samples. All other applications and species not yet tested.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: TLR2 Antibody is supplied in PBS containing 0.02 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C,4 °C

Informationen zur Lagerung: TLR2 antibody can be stored at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Details zu TLR2

Target: TLR2 (Toll-Like Receptor 2 (TLR2))

Andere Bezeichnung: TLR2

Hintergrund: TLR2 Antibody: Toll-like receptors (TLRs) are signaling molecules that recognize different microbial products during infection and serve as an important link between the innate and adaptive immune responses. These proteins act through adaptor molecules such as MyD88 and TIRAP to activate various kinases and transcription factors such as Protein Kinase C (PKC) alpha/beta and NF-κ,B. TLR2 can form heterodimers with either TLR1 or TLR6, and as a heterodimer can recognize a variety of bacterial and mycoplasma lipoproteins respectively.

Gen-ID: 7097

UniProt: O60603

Pathways: TLR Signalweg, Activation of Innate immune Response, Cellular Response to Molecule of Bacterial Origin, Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response, Toll-Like Receptors Cascades